This painting is a visual representation of the corpus callosum, a network of fibers that connect the two hemispheres of the brain. Females have a thicker corpus callosums on average, which means that the two hemispheres of their brains communicate better than in male brains. The end result is that females usually have superior verbal skills while men on the other hand have disconnected brains that allow them to compartmentalize thoughts in the different brain hemispheres and provide them with an advantage in math and spatial relationships.
The statue in the painting is split in half, representing the two hemispheres of the brain, the two square cube rock figures symbolize the two hemispheres of the brain. There is a semi-transparent triangle that shows the "golden ratio" of the Pythagorean theorem representing the left side of the brain or "logical" side being more predominant in most males.
Then two mammalian shaped figures are literal representations of the corpus callosum(s). The cloud at the top right is cut in half, to symbolize the two halves of the brain, the keys hanging off of the cloud indicate a metaphorical key for solving the differences between the sexes thought processes.